Stem Cell Transplantation

DESCRIPTION

A stem cell transplant also referred to as bone marrow transplant, is a procedure that is performed for certain types of cancer or in the cases when the bone marrow stops working and can’t produce enough healthy cells. The procedure involves replacing unhealthy blood-forming cells with healthy cells (called stem cells) in the body. Stem transplantation is of two types – one that involves using your own healthy cells (autologous transplant) and the other that involves using cells from a donor (allogeneic stem cell transplant). To eliminate blood cancer in the marrow and then restoring normal blood cell production doctors often use large doses of chemotherapy or radiation therapy. 

INDICATIONS

A stem cell replacement helps to generate healthy cells (new stem cells) in the body that can help in destroying the cancer cells directly. Also, it provides you with the opportunity to safely opt for heavy chemo and radiation and thus, gives you a better chance of fighting cancer. The procedure also helps in treating cancerous and noncancerous diseases including:

  •   Aplastic anemia
  •   Multiple myelomas
  •   Non-Hodgkin’s lymphoma
  •   Primary amyloidosis
  •   POEMS syndrome
  •   Chronic and severe leukemia
  •   Bone marrow failure syndrome
  •   Plasma cell disorders
  •   Immunity deficiency

PRE-PROCEDURE

Before you undergo stem cell transplantation your doctor will conduct a series of tests over a few days to check if you are physically fit for the cell transplantation or not. To infuse the transplanted stem cells and other blood products and medicines into your body your doctor will insert a long thin tube from your neck or chest into a large vein in the body. Once this pre-transplantation process and tests are done, the next step is the ‘conditioning regimen’ process in which you will undergo chemotherapy and radiation in order to:

  •   Remove the cancerous cells
  •   Make your bone marrow ready for new stem cells
  •   Eliminate any disease that might remain at the time of the transplantation
  •   Check your immune system Depending on the condition you’re being treated for, you might have to undergo both chemotherapy and radiation or any one of them.

You might feel following ill effects after the conditioning process:

  •   Ulcers
  •   Infertility
  •   Cataract
  •   Excessive bleeding
  •   Hair loss
  •   Nausea and vomiting
  •   Infection in the body
  •   Diarrhea
  •   Constant fatigue

DURING PROCEDURE

The treatment is performed once the conditioning is finished. This treatment doesn’t require anesthesia and the patient is kept awake. The procedure is carried out when the Donor’s stem cells are transferred to the patient’s body by infusion using the thin tube inserted before. Once the cells are transplanted into the body, they start producing new blood cells in a process called engraftment. This helps in recovering the blood count of the body. The blood cells contain a preservative called dimethyl sulfoxide which helps in guarding the cells. You might also be given some medications in order to reduce the adverse effects of this preservative. Some of the common symptoms you may feel include fever and chills, nausea, hives, diarrhea, and red urine.

POST PROCEDURE

Post-treatment you will be kept under observation and your doctor will continuously monitor your health. You might also have to stay longer in the hospital if there is any complication or infection. Before you leave the hospital, your doctor will make sure that you are able to eat food and drinks on your own without any difficulty, and there are no ill effects like fever, vomiting or diarrhea and your body have safe levels of blood counts. You may recover anywhere between 30 to 100 days after the transplant, depending on your prevalent condition and overall health.

RISK AND COMPLICATIONS

There might be a certain set of risks and complications that you will be already explained before beginning the procedure by your doctor. Some of the very common risks include:

  •   Infertility
  •   Infection in the body
  •   Development of new cancer cells
  •   Stem cell failure

MORE INFO

If you’re looking forward to undergoing a stem cell treatment and considering traveling to India you can be assured of state-of-the-art medical care and advanced treatment technologies present here. India has now become a preferred destination for medical tourism as the cost is relatively low as compared to the western countries but the treatment quality is substantially high. Normally, the treatment’s approximate Cost is  $6000 Duration: 30 – 45 Days. If you need any further information regarding this procedure, please feel free to contact us on +91-9999332093

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